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What is Triptorelin?

Triptorelin is in a class of medications called gonadotropin-releasing hormone (GnRH) agonists. It works by decreasing the amount of certain hormones in the body.

It is used to treat the symptoms associated with advanced prostate cancer and it is used to treat central precocious puberty (CPP; a condition causing children to enter puberty too soon, resulting in faster than normal bone growth and development of sexual characteristics) in children 2 years and older.

Triptorelin Test Analysis Results

Purity (HPLC): 98.0% min.
Appearance: White powder
Peptide Content (N%): ≥80.0%
Water Content(Karl Fischer): ≤6.0%
Acetate Content (HPIC): ≤15.0%
Single Impurity (HPLC): 1.0%max
Amino Acid Composition: ±10% of theoretical
MS(ESI): Consistent
Mass Balance: 95.0~105.0%
Specific Rotation (20/D): -65.0～-75.0°(c=0.5 1%HAc)

GnRH agonists uses:

1) Treatment of delaying puberty in individuals with precocious puberty.
2) Treatment of cancers that are hormonally sensitive and where a hypogonadal state decreases the chances of a recurrence. Thus they are commonly employed in the medical management of prostate cancer and have been used in patients with breast cancer.
3) Sex reassignment of male to female transsexuals.
4) Management of female disorders that are dependent on estrogen productions. Women with menorrhagia, endometriosis, adenomyosis, or uterine fibroids may receive GnRH agonists to suppress ovarian activity and induce a hypoestrogenic state.
5) Temporary Suppression of Fertility in Male Dogs
6) Severe cases of congenital adrenal hyperplasia
7) Induction of Ovulation in Mares

Triptorelin uses

Triptorelin is used to treat advanced prostate cancer in men. It is a hormone that is similar to the one normally released from the hypothalamus gland in the brain. When given on a regular basis to men, triptorelin decreases testosterone levels which helps treat prostate cancer.

Triptorelin side effects

Common triptorelin side effects may include: hot flashes; pain, swelling, itching, or redness where an injection was given; headache, bone pain, pain or swelling in your legs; vaginal bleeding; nausea, vomiting, diarrhea, upset stomach; decreased interest in sex, impotence, trouble having an orgasm; cold or flu symptoms (stuffy nose, sneezing, cough, sore throat, ear pain).

Triptorelin Dosage:

For the purposes of post-cycle therapy, it is common practice to inject 100mcg subcutaneously after completion of a steroid cure, for example, on the follow-up injection day of the last steroids injection.

If you use several steroid cures a year, then at least 4 months have to pass between the administration of a triptorelin injection to avoid symptoms of chemical castration.

Triptorelin Storage

Store at -20°C. The product is hygroscopic and must be protected from light. Following reconstitution, aliquot and store at -20°C.